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For patients with migraine-associated nausea, photophobia, and phonophobia at baseline, there was a lower incidence of these symptoms at 2 and 4 hours following administration of dihydroergotamine mesylate nasal spray compared to placebo

This precaution is standard for most cosmetic actives where systemic absorption and fetal or infant exposure have not been formally studied

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Analysis of the analgetic and anti-inflammatory effects or rimazolium, a pyrimido-pyrimidine derivate, compared with that of prostaglandin synthesis inhibitors and morphine, Drugs Exptl Clin