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Description

Cloning and characterization of a putative human serine/threonine protein kinase transcriptionally modified during anisotonic and isotonic alterations of cell volume

Zaki et al., 2019

In an MCF-7 xenograft model, imaging assays showed that 8 h after administration, a high concentration of aptamer-modified PROTACs was observed in tumour tissues, while no signal was detected from the unmodified PROTACs