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These results reinforce the role of GCLC in regulating not only GSH synthesis but also mitochondrial integrity and cell viability under oxidative stress [34,35,36]

London, UK: BMJ Group, RPS Publishing, 2009 17

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As lung elasticity declines, the respiratory system becomes weaker, resulting in a reduction in vital capacity and arterial oxygen pressure (Sharma and Goodwin, 2006)