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A caffeine overdose happens when you ingest more caffeine than your body can safely process

Mice lacking TRPV4 channels are less sensitive to mechanical stress (131) whereas mice with ablated TREK/TRAAK channels are hypersensitive to mechanical forces and local pH changes (136)

Consult with a qualified healthcare provider before beginning any supplementation protocol.

Similarly, in an article published in Muscle and Fitness, glutathione combined with L-citrulline boosted nitric oxide production (NO) better than placebo or L-citrulline alone.20 Nitric oxide is well known to dilate blood vessels improving blood flow and oxygen delivery to muscles and tissues