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For instance, microglial depletion disrupts the growth of long projecting axons beyond the lesion after spinal cord injury in neonatal mice, suggesting they play an active role in regeneration [438]

However, they may be toxic at high concentrations by increasing ROS formation (Koivula and Eeva, 2010)

M.CampbellS

First, it has been shown that in DA-resistant tumors the reduction of DRD2, previously associated with resistance, is accompanied by a low level of FLNA ( In vitro experiments starting from this experimental observation demonstrated that alterations of FLNA levels in primary cultured prolactinoma cells by gene silencing or overexpression resulted in corresponding modifications of DRD2 levels, demonstrating that these two events are causally related