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Visceral hypersensitivity, serotonin dysregulation, gut-brain axis dysfunction, and central/peripheral nervous system alterations are implicated in IBS-C pain, while FC pain is less studied and may be primarily linked to colonic distension and motility dysfunction

Owing to the implications of these findings, our six laboratories have examined key findings of Bhattacharjee et al

Relationship between brain lipid metabolism and senescence The role of lipids in the brain Lipids constitute approximately 60% of the brain's dry mass, with a marked concentration within neuronal membranes and the myelin sheath, which functions as a critical insulator for axonal conduction

Acetyl-CoA and NADPH generated from glycolysis directly fuel DNL, representing a primary metabolic link between glucose and lipid pathways