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Aging Cell 20 (12), e13522

doi: 10.1155/2019/4273261

COXs are abundantly expressed in neurons and microglia across various animal species ( in vivo and in vitro experimental showed that tumor necrosis factor- (TNF-)-mediated BBB breakdown is linked to COXs up-regulation the expression and activity of matrix metalloproteinases (MMPs) (Sugimoto et al., 2009)

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