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glutathione metabolism and its role in hepatotoxicity

glutathione metabolism and its role in hepatotoxicity Changes Content in Liver Diseases: An Update Two hit model during APAP-induced

Two hit model during APAP induced hepatotoxicity. The first hit Download Scientific Diagram Regulation of hepatic glutathione synthesis: : The FASEB Journal Biochemical pathway model of glutathione metabolism. Download Scientific Diagram The Key Role of GSH in Keeping the Redox Balance in Mammalian Cells: Mechanisms and Significance of GSH in Detoxification via Formation of Conjugates

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Description

Mechanistically, we observed that FGF21 enhances the mitochondrial uptake of glutathione (GSH), an essential redox metabolite, by targeting SLC25A39, a recently identified mitochondrial GSH transporter

glutathione metabolism and its role in hepatotoxicity Changes Content in Liver Diseases: An Update Two hit model during APAP-induced

Evidence is Level II (small RCTs)

glutathione metabolism and its role in hepatotoxicity Changes Content in Liver Diseases: An Update Two hit model during APAP-induced

Chen D, Chu B, Yang X, Liu Z, Jin Y, Kon N, Rabadan R, Jiang X, Stockwell BR, Gu W

glutathione metabolism and its role in hepatotoxicity Changes Content in Liver Diseases: An Update Two hit model during APAP-induced

Inhibition of glutaminolysis, a crucial component of ferroptosis, attenuates I/R-related heart injury [20]

glutathione metabolism and its role in hepatotoxicity Changes Content in Liver Diseases: An Update Two hit model during APAP-induced
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