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Cibinetide (ARA 290) for the treatment of small fiber neuropathy in sarcoidosis

Nanobody-35 (Nb35) and HRV 3 C protease were in-house purified from E

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This led to the assumption that the primary receptors mediating weight loss for this target class were AMYRs, yet, dual agonists are reported to have higher efficacy than AMYR selective agonists 2,10,11,12