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Dysregulation of miR-15a-5p, miR-497a-5p and miR-511-5p is associated with modulation of BDNF and FKBP5 in brain areas of PTSD-related susceptible and resilient mice

For each PCR condition, SYBR Green I Master (Roche Diagnostics, Mannheim, Germany) and the following primers were used: FTL: 5-TACGAGCGTCTCCTGAAGATGC-3 and 5-GGTTCAGCTTTTTCTCCAGGGC-3, PTGS2: 5- ATATGTTCTCCTGCCTACTGGAA -3 and 5-GCCCTTCACGTTATTGCAGATG-3, ACSL4: 5- TGGAAGTCCATATCGCTCTGT -3 and 5- TTGGATACAGCATGGTCAAA-3, HMOX-1: 5- CAACATCCAGCTCTTTGAGGA -3 and 5- T GGGCAGAATCTTGCACTTTG-3, Nrf-2: 5- TACTCCCAGGTTGCCCACA-3 and 5- CATCTACAAACGGGAATGTCTGC-3, GSTP1: 5- TACACCAACTATGAGGCGGG-3 and 5- AGCGAAGGAGATCTGGTCTC-3

The medication provides relief for 4 to 6 hours in most patients

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