nadph oxidase glutathion reductase Schematic representation of NAD(P)H activity. This enzymes Glutathione system with synthesis routes

1 Introduction Autoimmune diseases are a heterogeneous group of disorders caused by the misdirection of the immune system toward its host, and the presence of autoantibodies is a common feature of autoimmune diseases ( Given the limited understanding of the complex molecular mechanisms underlying autoimmune diseases, it is widely accepted that a combination of genetic predisposition and environmental factors disrupts immune tolerance (6), This disruption leads to the clonal expansion of autoreactive B and T cells, resulting in the production of autoantibodies that trigger autoimmune inflammation and the pathological attack on the bodys tissues

Reconstructing the Society of Ancient Israel

2013;8(11):e78368

Piedade et al