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This action increases: Antioxidants production Oxygen delivery Immune responses Local or tissue perfusion (volume of blood flow within tissue) A recent narrative review observes ozone contains antiviral properties that may counter SARS-CoV-2

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The ability of viral variants to evade immunity was brought to the center stage by the emergence of the Omicron strain of SARS-CoV-2, which was first reported in November 2021