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Consult the labeling of concomitantly used drugs to obtain further information about interactions with PPIs

B12 injections are useful if you: Have a confirmed B12 deficiency on recent bloods Are vegan or vegetarian and not supplementing reliably Are over 60 or take medications that reduce B12 absorption (metformin, PPIs) Have had bariatric surgery or gut surgery Have low-normal B12 with persistent fatigue and want to see if an injection helps Ill send you to your GP first if you: Have severe or worsening fatigue without explanation

Vitamin B12 is often included in the mix to promote energy and aid in forming new, healthy cells in the body

Other users reported temperature-related symptoms such as chills, feeling cold, hot flashes, and fever-like sensations