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Osteoblasts and osteoclasts functions are regulated by a system of neuropeptides from the central nervous system, which helps maintain the balance between bone formation and bone resorption (277)

This study demonstrated that MgIG significantly inhibited the protein expression of COX-2 and 5-LOX, key enzymes in both metabolic pathways of arachidonic acid induced by LPS (Xie et al., 2015) (Figure 4)

Liu X, George GC, Tsimberidou AM, Naing A, Wheler JJ, Kopetz S , Fu S, Piha-Paul SA, Eng C, Falchook GS, Janku F, Garrett CR, Karp DD, Kurzrock R, Zinner R, Raghav KPS, Subbiah V, Meric-Bernstam F, Hong DS, Overman MJ