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4(1): 35-75 ( Article history: Received 12 March 2017

Lactoferrin and oral pathologies: A therapeutic treatment

[12] Gastric acid-suppressing agents (proton-pump inhibitors and H-receptor antagonists) diminish dietary B12 liberation from protein complexes, a pharmacodynamic interaction that can exacerbate underlying deficiency

In models, moderate ROS levels in HepG2 and Huh7 cells activate ERK and AKT, leading to the transcriptional induction of mesenchymal markers (Snail, vimentin) and matrix metalloproteinases (MMP-2/9), while concurrently repressing epithelial E-cadherin [91]