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For coffee concentration experiment, pure water, 40% (v/v) coffee extract, and 60% (v/v) coffee extract were allowed ad libitum (n=6 per group in each experiment)

Pharmacotherapies that target these more protracted changes have the potential to greatly improve both treatment retention and functional outcomes during recovery

Fibrillation of -synuclein leads to the formation of a cross beta pleated sheet which causes cellular toxicity by creating pores in the membrane, inducing misfolding of other proteins and eliciting other signalling pathways which results in loss of cellular homeostasis

Jedidi S, Sammari H, Selmi H et al (2021) Strong protective effects of Salvia officinalis L