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Peroxynitrite (ONOO - ) is a reactive species generated by the diffusion-controlled reaction of superoxide and nitric oxide and has been suggested to contribute to -cell damage in response to pro-inflammatory cytokines (41, 42)

10.1016/j.biopha.2020.110917 97 LinY.-T.ShiQ.-Q.ZhangL.YueC.-P.HeZ.-J.LiX.-X.et al (2022)

For many individuals battling these invisible illnesses, the body's natural detoxification pathways become overwhelmed, leading to a steady buildup of metabolic waste, bacterial endotoxins, and environmental irritants that continuously stoke the fires of the immune system and prevent true recovery

Here are the keyways LDN may contribute to weight loss: Naltrexone Reduces Insulin Resistance Studies indicate that Naltrexone can significantly lower fasting insulin levels