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Using this approach, we showed that the time course for the onset of depression-like behavior in rats is paralleled by dampened hippocampal neurogenesis and neuronal maturation (Lussier et al., 2013)

Journal of Neuroscience Research, 83(7), 1252-1261

This involves isolating immune cells with high mutational loads and specifically inhibiting this pathway to assess its contribution to the IFN signature and T cell exhaustion