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This limitation hinders our progress in translating these promising active substances into clinical drugs

We, therefore, took advantage of MIFC, which combines fluorescence microscopy and flow cytometry and is a suitable means for the analysis of immune synapse formation (2C,D)

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This review aims to systematically expound on these dual physiological and pathological roles, arguing that such disease-specific metabolic alterations not only provide biomarkers but, more importantly, unveil targetable vulnerabilities, thereby positioning amino acid metabolism as a strategic frontier for developing novel therapeutics across liver diseases