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However, this method has problems associated with highly complicated reaction steps and the use of a heavy metal such as lead tetraacetate (Pb(CH COO) )

The benefits of LC (50 mg/kg/day) administered orally to 20 participants for 30 days on PD were studied by Kosan et al

(More information) L-Carnitine supplementation is indicated for the treatment of primary systemic carnitine deficiency, which is caused by mutations in the gene that codes for the carnitine transporter, OCTN2

Early, small trials suggested a beneficial effect of ALCAR with respect to cognitive decline (98-100), whereas later, larger trials found little-to-no effect compared to placebo (101-103)