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The multifaceted actions of (-)-Vestitol and Salviolone, particularly their synergistic effects, highlight their potential as a novel therapeutic strategy for AD

Over time, the genome becomes increasingly dysregulated: DNA regions that should be silent become noisy, protective genes are switched off, and chromatin, the scaffold of DNA wrapped around histones (imagine them like packaging bundles), becomes condensed and brittle, losing its flexibility

In studies employing this approach, the risk of cancer progression and recurrence triggered by senescent cancer cells was significantly mitigated 63