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Other symptoms can include peripheral neuropathy , characterised by weakness and pain in the limbs, and mood disturbances due to its role in neurotransmitter synthesis

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It means the context behind each compound matters as much as the mechanism

During the degranulation and release, perforin polymerizes and forms pores in the target cell membrane to facilitate granzymes delivery into target cells, inducing apoptosis through different pathways, including caspases-3/7 activation, cytochrome C release from mitochondria driven by Bak/Bax, and IL-1 regulation by caspase-1 [32]