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Research Applications Localized muscle growth and hypertrophy research Muscle injury repair and regeneration studies Satellite cell activation and proliferation research IGF-1 receptor signaling pathway studies Muscle protein synthesis and anabolism research Acute metabolic response research Muscle hyperplasia (muscle fiber number increase) studies Age-related muscle loss and sarcopenia research Exercise recovery and adaptation studies Body composition optimization research Comparative IGF analog pharmacology research PI3K/Akt/mTOR pathway activation studies Safety Profile The safety profile of IGF-1 DES in humans is poorly characterized due to the absence of rigorous clinical trials and regulatory oversight of this research compound

The blood-brain barrier after stroke: Structural studies and the role of transcytotic vesicles

10.3389/fimmu.2021.633486 72

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