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NRF2 protein stability is tightly regulated and its two main regulators are i) Kelch-like ECH-associated protein 1 (KEAP1) in the cytoplasm and ii) BTB and CNC homology 1 (BACH1) in the nucleus

Singh S, Kumar V, Datta S et al (2020) Glyphosate uptake, translocation, resistance emergence in crops, analytical monitoring, toxicity and degradation: a review

The fact that STARD7 acts as a tumor suppressor gene in Wnt-driven tumor development was unexpected given the fact that we and others showed that STARD7 is overexpressed in clinical cases of colon cancer known to show constitutive Wnt signaling in most cases (Zhao et al, 2023)