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Short-term treatment may provide targeted relief, however, combining antibiotics with probiotics can help reduce the harmful impact on the microbiota, while caution is suggested due to potential inflammatory responses [96102]

Imaging studies, such as computed tomography of the abdomen, should be carried out, as well as upper endoscopy, to rule out any obstruction at the level of the gastrointestinal tract (Fig

The accumulation and loss of epigenetic alterations in response to anticancer therapy may also provide temporary, plastic adaptations beneficial for survival (Gatenby et al., 2009