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Schanzer et al., 2014)

The effect of short-term strength training on human skeletal muscle: the importance of physiologically elevated hormone levels

Conformational changes of these conserved residues especially the transmission switch residues F272 6.44 and W276 6.48 have been suggested to link the extracellular agonist-binding to the cytoplasmic receptor activation and G protein-coupling for class A GPCRs (Supplementary Fig