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[DOI] [PMC free article] [PubMed] [Google Scholar] 148.Jimnez-Flores L.M., Lpez-Briones S., Macas-Cervantes M.H., Ramrez-Emiliano J., Prez-Vzquez V

Although not studied, an interaction of topiramate and valproic acid may exacerbate existing defects or unmask deficiencies in susceptible persons (see Contraindications and Hyperammonemia and Encephalopathy Associated with Concomitant Topiramate Use as previously mentioned)