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In Figure 2, we compare the redox status in the serum of women without (control) or with a mood disorder and did not observe any statistical difference in reactive species analyses (Figure 2A), SOD activity (Figure 2B), and glutathione reduced (Figure 2C)

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269 These findings illustrate that PERK signaling exerts dose-, duration-, and context-dependent effects, complicating efforts to therapeutically manipulate this pathway

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