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The resulting decline in SCFAs, particularly butyrate, diminishes activation of FFAR2/FFAR3 receptors on enteroendocrine L-cells and lowers GLP-1 secretion

In the mitochondria, pyruvate dehydrogenase requires TPP to convert pyruvate into acetyl-CoA, which enters the citric acid cycle

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The vascular endothelium and coagulation: homeostasis, disease, and treatment, with a focus on the von willebrand factor and factors VIII and V