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Lactate was also found to signal through specific G-protein coupled receptors expressed in neurons and glial cells, suggesting a possible role in neurotransmission, neurovascular coupling, and brain energy metabolism (Morland et al., 2015)

The handling Editor declared a shared affiliation, though no collaboration, with three of the authors, ZL, JQ, and JC, at the time of review

More recent studies suggest that the blood concentration of trimethylamine N-oxide (TMAO), generated from trimethylamine-containing nutrients like dietary choline, rather than that of choline, might influence the risk of cardiovascular events (see Safety)

roughly 1.5 million people died from this infection in 2020 ( Mycobacterium tuberculosis (M