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Bulletin of the World Health Organization

Front Oncol (2020) 10:787

Gut microbes impact stroke severity via the trimethylamine N-oxide pathway

Following structural damage and functional impairment of the muscle tissue, myofibrillar rupture and extravasation of intracellular proteins such as myoglobin, creatine kinase (CK), and lactate dehydrogenase (LDH), into the extracellular medium, trigger the local inflammatory response [47, 50,51,52]