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Thus, it is likely that the intake of foods and/or beverages with high levels of exogenous AGEs create more health problems than endogenously produced AGEs, although both exogenous and endogenous AGEs are similar in their biological functions and potentially act synergistically to stimulate oxidative stress, inflammation, and cellular damage, contributing to detrimental pathophysiology 2,3,4,24

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Bar colors indicate the number of genes associated with each biological process