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Since Humira is a specialty drug, it is likely to be on the highest drug tier, meaning the most expensive copay

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and Group 3, Tbx1 +/ -unique genes, those that responded to treatment exclusively in the Tbx1 +/ samples (n = 823) (Fig 5A, Table S2)

In the CY 2024 PFS final rule (88 FR 79047 through 79064), we finalized the ( date of the initial refund report to manufacturers, the date for subsequent reports, method of calculating refunds for discarded amounts in lagged claims data, method of calculating refunds when there are multiple manufacturers for a refundable drug, increased applicable percentages for certain drugs with unique circumstances, and a future application process by which manufacturers may apply for an increased applicable percentage for a drug, which would precede proposals to increase applicable percentages in rulemaking