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The ratio of CD8\CD4 increases in blood samples obtained from vitiligo patients (Kaur et al., 2017), which is directly correlated with the severity and activity of the disease (Rashighi et al., 2014), and is considered a marker of poor treatment response

A pediatric case definition for myalgic encephalomyelitis and chronic fatigue syndrome

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For instance, the proangiogenic factors released by cancer cells to promote angiogenesis and tumor development may be enriched by IL-6 produced by MSCs