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In fact, alterations can also be found in euthymia, when patients show to have greater levels of IL-8 in cerebrospinal fluid and monocyte chemoattractant proteins [129]

Therefore, strategies for mitochondria-mediated ferroptosis in IDD exhibit notable research and application potential (Fig

In addition to estrogens, OVX also depletes other hormones (androgens, LH, GnRH, FSH), which play an important role in menopause and affect brain function [215]