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Revised: 11/2018 Full Prescribing Information 1

Although currently WHO uses expression of specific transcription factors as basis of PitNET classification (six morphologically distinct types based on transcription factors with three main cell lineages: SF1 (gonadotroph cells), PIT1 (lactotroph, somatotroph, mammosomatotroph, and thyrotroph cells), and TPIT (corticotroph cells) they can be characterised according to the type of synthesised hormone and distinct clinical symptoms [3]

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