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The ECM significantly influences cancer progression by providing biochemical and biomechanical signals that regulate cell behavior, which includes proliferation, invasion, and resistance to therapy ( The role of the ECM in tumorigenesis remains complex and not fully understood

These results are consistent with data published by others (Florez-Duquet et al

The auxiliary gas heater and capillary temperatures were 450 C and 275 C, respectively, with an ion spray voltage of 2.5 kV

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