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The area under the ROC curve (AUC) was applied to evaluate the predictive performances of the test biomarkers

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On the other hand, Kupffer cells, upon activation by endotoxins (including lipopolysaccharide, LPS) or superoxide anions (O 2 ), will then produce more ROS through stimulation of NADPH-dependent oxidases (NOXs), and the redox-sensitive transcription factor nuclear factor-B (NF-B)-mediated pro-inflammatory storm of cytokines, chemokines, and cell adhesion molecules (CAMs) [36]

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