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It is associated with the loss of dopaminergic cells in the substantia nigra, which is thought to result from Lewy body inclusions formed by alpha-synuclein aggregation (64)

Ultimately, this research should include large-scale clinical intervention studies in humans with an integrated approach that combines microbiome, multi-omics, metabolomics and immunological readouts, and compares administration formulations and routes

Brouwers MC (2022) Fructose 1-phosphate, an evolutionary signaling molecule of abundancy

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