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Linear modeling using the limma package was conducted to compute the genes for each dataset that were significantly changed between experimental groups, as defined by a p-value smaller than 0.05 and these genes were mapped to biological pathways using PathVisio with WikiPathways content [11], [12], [21]

Gene therapy strategies that activate the Nrf2/ARE pathway in astrocytes have been shown to reduce oxidative stress and provide neuroprotection to DA neurons in both in vitro and in vivo settings (Williamson et al., 2012)

Le glutathion est prsent l'tat naturel dans notre organisme et joue le rle de principal antioxydant pour chaque cellule de notre corps