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Nature (2004) 427:3604.10.1038/nature02246 86 GilabertJAParekhAB

The disease is caused by the abnormal expansion of the GAA repeat sequence in intron 1 of the FXN gene, leading to the reduced expression of the mitochondrial protein frataxin

Genetic and RNA studies can provide better understanding of metabolic pathways in Spirulina to allow for better modification of its strains that for ease of cultivation and processing