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This migration is mediated through the FAK-paxillin pathway, a signaling cascade that controls how cells move and attach to surrounding tissue

The most common example of an autoimmune condition is Pernicious Anemia , where the immune system attacks cells present in the stomach, which are responsible for producing intrinsic factors

The original murine antibody was humanized, and CM313 has been shown to inhibit some of the enzymatic activities of CD38