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360,361 Third, long-term use of SSRIs can increase 5-HT transmission in the LC, 362 thereby increasing the release of GABA to exert inhibitory effects on NA neurons

Therefore, more selective SLC7A11 inhibitors and genetic targeting strategies, including small interfering RNAs (siRNA) and small guide RNAs (sgRNA), would be ideal for clinical purposes

459, pp

Power WJ, Ghoraishi M, Merayo-Lloves J, Neves RA, Foster CS (1995) Analysis of the acute ophthalmic manifestations of the erythema multiforme/Stevens-Johnson syndrome/toxic epidermal necrolysis disease spectrum