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FIGURE 2 Further research suggests that resistance mechanisms to AmB in Leishmania involve complex interactions between genetic mutations and metabolic changes

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This patient's exclusive use of lisinopril and fetal misshapen cranium make impaired maternal prostaglandin synthesis unlikely

TMAO also decreases the mRNA expression of Niemann-Pick C1 (NPC1L1) and ATP-binding cassette (ABC) G5/G8, inhibiting intestinal CHO absorption (Koeth et al., 2013)