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Keywords: obesity, therapeutics, nicotinamide N-methyltransferase, inhibitors, weight loss Graphical abstract 1

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If you have malabsorption syndrome (such as short bowel syndrome, certain bariatric surgery patients, chronic pancreatitis, or celiac disease that severely impairs nutrient uptake), you might need these injections indefinitely to prevent recurrent deficiencies

By the mid-2010s, 5-Amino-1MQ emerged as one of the compounds used in experimental NNMT-related research investigating metabolic signalling and enzyme regulation