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To achieve tHcy concentrations as low as possible ( C mutation in the MTRR gene creates an SF2/ASF binding exonic splicing enhancer, which leads to pseudoexon activation and causes the cblE type of homocystinuria

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Patients who do not tolerate GLP-1 medications: those who had gastrointestinal side effects from semaglutide or tirzepatide and want to understand other options to discuss with a provider

Evidence-Base Disclosure The published evidence base for AOD-9604 consists predominantly of preclinical research animal models (often rats or mice) and in vitro cell-culture experiments