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For example, epidemiological studies have reported that co-administration of certain medicines may increase or reduce the risk of Chronic Obstructive Pulmonary Disease (COPD)

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Copper(II) generates ROS and RNS, impairs antioxidant system and damages membrane and DNA in human blood cells

(3) Combination therapies: combining oxidative cell death inducers with conventional treatments, such as chemotherapy and radiotherapy, can synergistically enhance treatment effectiveness, potentially overcoming drug resistance and improving patient outcomes