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Description

DNA methylation changes at specific loci hold promise as potential biomarkers for Huntingtons disease (HD), as such alterations are characteristic of the condition

Importantly, distinct lactylation patterns demonstrate variable effects at different stages of these cardiovascular diseases, either aggravating or mitigating the progression of the disease (Figs

To test this possibility, we acquired two-dimensional (2D) 13 C- 13 C (CC) ssNMR data and observed unambiguous contacts between the long hydrophobic side chains of I22 and Y25 (Extended Data Fig