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RCT randomized controlled trial, PA physical activity, w week, d day, RT resistance training, CT concurrent training, TR training, CP collagen peptide group, PLA placebo group, PT patellar tendon, AT Achilles tendon, CSA cross-sectional area, MVC maximal voluntary contraction, KE knee extension, KF knee flexion, 1RM one-repetition maximum, FFM fat-free mass, VL vastus lateralis, RF rectus femoris, INT vastus intermedius, SQ squat, DL deadlift, BP bench press, R bent-over row, MIS Maximal isometric squat, SJ Squat jump, LQ left quadriceps, RQ right quadriceps, post/24 h/48 h change scores referring to values obtained preceding muscle damage induced exercise Risk-of-Bias Assessment To evaluate RCTs risk of bias, the Physiotherapy Evidence Database (PEDro) scale was used as an equivalent alternative to the Cochrane risk of bias tool [43]

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Subsequent cellular assays demonstrate that AOD-9604 upregulates the transcription of 3-adrenergic receptor RNA in isolated adipocytes