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Juhasz G, Kekesi K, Emri Z, et al

We have also reported that the hepatic restoration was associated to antioxidant, antiapoptotic, antifibrogenic and mitochondrial-protective effects of IGF-I[230234]

These changes correlate with increased GSH levels and decreased ACSL4 expression, thus mitigating ferroptotic cell death in IL-1stimulated chondrocytes and preserving cartilage integrity (187)